FDA chief: Cuts threaten drug approvals

Lorraine McCartin's breast cancer has been in remission for more than a year, thanks to a drug called Kadcyla that the Food and Drug Administration only recently approved solely for patients with late-stage breast cancer. In 2010, McCartin, 56, of Hanson...

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The Ticker

787 ready for takeoff Boeing said it sees commercial flights of its grounded 787 jets resuming "within weeks" even though it has not pinpointed the cause of battery overheating. A Boeing exec said a new design for the lithium-ion battery system has...

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Always sunny in North Andover

This custom Royal Barry Wills Associates home in North Andover is an elongated Cape with three distinct wings that's positioned for maximum exposure to the sun. Designed in 1985 by Richard Wills, son of the late Melrose-born architect Royal Barry Wills,...

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The Ticker

Geithner book said to recount financial crisis Former Treasury Secretary Timothy Geithner, right, has a book deal with Crown Publishers, an imprint of Random House. Geithner's book, currently untitled, is scheduled for 2014 and will provide a "behind-the-scenes"...

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They’re married all year – to the IRS

Tax season is upon us and the Herald's TaxSmart experts are here each Friday to help. Today, Norwood CPA Robert Fineman discusses how married couples can cope with filing statuses. I got married toward the end of 2012. My wife and I had already bought...

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Rooms with a view of St. Pat’s Day fun

Rooms with a view of St. Pat's Day fun Once a year, a select group of Southie residents have front-row seats to the neighborhood's storied St. Patrick's Day parade. Tens of thousands flood the sidewalks and fill the windows along Broadway, East Fourth,...

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Cocktails will flow year-round in Frost’s cool setting

Customers can expect a cool reception at Boston's newest attraction this spring. Frost Ice Bar — where everything but the floor and ceiling will be made of ice — is under construction in a building near Faneuil Hall in preparation for a June opening....

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Roxbury grocer aims to triple size with $44M plan

Madison Park Development Corp. and Tropical Foods International hope to start construction by July on their $44 million mixed-used project in Roxbury's Dudley Square. The companies have filed a "letter of intent" to the Boston Redevelopment Authority...

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Apple CEO required to testify in NY e-books case

NEW YORK — Apple CEO Tim Cook has been ordered to testify in a New York court case the Justice Department brought against the company over the pricing of e-books for consumers. Federal Judge Denise Cote on Wednesday granted a government request to depose...

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Miami New Times rejects MLB request

MIAMI — The Miami New Times has rejected a request from Major League Baseball for records that the alternative newspaper obtained for a story that alleges several players received performance-enhancing drugs from a now-closed anti-aging clinic. New...

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Leap jumps to capture next step in motion control

AUSTIN, Texas — In a bustling tent set up in a parking lot here at the South By Southwest Interactive Festival, people are pointing their hands and gesturing with chopsticks as they guide various actions on a dozen computer screens. Some of the sharpest...

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Report: More youth use smartphones as route to Web

CHICAGO — Keep computers in a common area so you can monitor what your kids are doing. It's a longstanding directive for online safety — but one that's quickly becoming moot as more young people have mobile devices, often with Internet access. A new...

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Yo! kicks into gear as Fung Wah still stalled

With Fung Wah still out of service, Greyhound revved up a bid to dominate the discount passenger bus market between Boston and New York City with yesterday's expansion of its Yo! brand. "Fung Wah had been a thorn in Greyhound's side for years, so they...

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Judge strikes down NYC ban on supersized sodas

NEW YORK — A judge struck down New York City's pioneering ban on big sugary drinks Monday just hours before it was supposed to take effect, handing a defeat to health-minded Mayor Michael Bloomberg and creating uncertainty for restaurants that had already...

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Asia markets reverse early gains on China worries

BANGKOK — Asian stock markets dropped Tuesday, dragged down by new worries about China's recovery and Europe's doldrums. Japan's Nikkei did an about-face after spurting higher in the morning. After hitting 12,461.97, an intraday high not seen in more...

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The Ticker

Dutch airliner partly fueled by cooking oil A Dutch airliner is flying from New York to Amsterdam on a fuel mix that includes leftover oil from frying Louisiana's Cajun food. The KLM flights from Kennedy Airport are powered by a combination of 25 percent...

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Fine-tuning fine dining preferences

A Cambridge startup is making it easier for diners to choose from the 200-plus eateries participating in Boston's Winter Restaurant Week this month. Nara Logics aims to become for restaurants what Pandora is for music. After users of Nara's website...

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Phoenix's BizNasty scoring on Twitter

PHOENIX — EDITOR'S NOTE — Phoenix Coyotes enforcer Paul Bissonnette adopted Twitter reluctantly but has now become an unlikely star on the social media network. In keeping with Twitter style, this story about Bissonnette's online personality is broken...

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Producers fish for 
ideas at trade shows

Boston is a food mecca this week. Exhibiting companies from 46 countries have descended on the Hub for the three-day International Boston Seafood Show/Seafood Processing America that starts today. More than 19,000 attendees are expected to pack the...

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Co. offers cash rewards 
for comparison shopping

Co. offers cash rewards 
for comparison shopping There was a time when small businesses took out ads in the Yellow Pages to get noticed. Today, they find themselves competing with national companies for attention online. But a new website founded by...

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Catholic faithful get wired for papal selection

The vote to select a new pope may remain shrouded in secrecy — the Vatican even installed special jamming equipment to block cellphone use inside the Sistine Chapel — but for the Catholic faithful who want to follow the papal election in real time, there's...

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